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HU Credits:
5
Degree/Cycle:
1st degree (Bachelor)
Responsible Department:
Pathology Department
Semester:
1st Semester
Teaching Languages:
Hebrew
Campus:
Ein Karem
Course/Module Coordinator:
Dr. Yakov Fellig
Coordinator Office Hours:
Sunday-Thursday 17:00-18:00, by appointment
Teaching Staff:
Prof Eli Pikarsky
Prof Yoav Sherman
Prof Michael Steinitz
Dr. Yakov Fellig
Alexander Maly
Dr. Karen Meir
Eliahu Golomb
Tzahi Neuman
Maya Moss Yishay
Judith Diment
Course/Module description:
This course is presented in a frontal lecture format with alternating two-hour long and one-hour long lectures consisting of: introductory lectures into the general pathology of cellular inury/adaptation, inflammation, neoplasia, and immune processes, and also pathological manifestations of circulatory disorders, metabolic diseases and infectious diseases. In addition there are 4 labs, two-hour long each, that include a slide seminar compatible with previous frontal lectures, divided into slides overview by the assigned lecturer, using a central microscope connected to several projectors, and independent work with a personal computer per each student and virtual pre-scanned slides. A bibliography is provided for supplemental reading and histopathology atlas. An informal visits of small groups (about 10-15 students each) to the pathology department are also conducted, usually during the second part of each lab. During these visits the students are instructed by one of the lecturers about the nature of the work in a pathology department by going through all the stages of processing surgical specimens, handling frozen sections and cytology specimens. Subject to prior coordination, students (up to 10 at once) may observe autopsies
Course/Module aims:
Recognize physiological, biochemical and immunological abnormalities and correlate them with morphological changes in various organs and the clinical findings
Learning outcomes - On successful completion of this module, students should be able to:
• Recall pathological terminology
• Associate cellular changes observed with the disease process
• Outline cellular responses and adaptations to injury
• Describe the pathological processes observed in inflammation, repair, circulatory disorders, infectious diseases, autoimmune diseases and radiation injury
• Recognize certain genetic and metabolic diseases
• Explain the systems used to classify neoplasms, and recognize common molecular-genetic alterations and risk factors underlying neoplasia
Attendance requirements(%):
80
Teaching arrangement and method of instruction:
Lectures and Labs
Course/Module Content:
Pathological processes including;
• Cellular responses to injury, cellular adaptation and cell death
• Acute inflammation, chronic inflammation and repair
• Neoplasia terminology and classification. Genetic and environmental causes of neoplasia
• Mechanisms of disease underlying circulatory disorders: congestion, edema, hemorrhage, thrombosis, embolus and infarction
• Genetic diseases: single gene disorders, inherited metabolic diseases and structural disorders
• Diseases of the immune system: amyloidosis, hypersensitivity, autoimmune diseases: eg. SLE, Sjogren syndrome and Scleroderma
• Morphological changes in various infectious diseases
• Radiation injury
Required Reading:
Robbins and Cotran: Pathologic Basis of Disease (Kumar, Abbas, Fausto, Aster), Saunders Elsevier, 9th Edition, 2015
Additional Reading Material:
Course/Module evaluation:
End of year written/oral examination 100 %
Presentation 0 %
Participation in Tutorials 0 %
Project work 0 %
Assignments 0 %
Reports 0 %
Research project 0 %
Quizzes 0 %
Other 0 %
Additional information:
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