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HU Credits:
3.5
Degree/Cycle:
1st degree (Bachelor)
Responsible Department:
Medicine
Semester:
2nd Semester
Teaching Languages:
Hebrew
Campus:
Ein Karem
Course/Module Coordinator:
Dr. Yakov Fellig
Coordinator Office Hours:
Teaching Staff:
Prof. Eli Pikarsky,
Dr. Yakov Fellig,
Dr. Tal Keidar,
Dr. Karen Meir,
Dr. Eliahu Golomb,
Dr. Tzahi Neuman
Course/Module description:
This course is presented in a frontal lecture format consisting of: introductory lectures into the general pathology of cellular injury/adaptation, inflammation and tissue repair, neoplasia, immune processes, amyloidosis, hemodynamic disorders, thrombosis and shock, genetic and metabolic diseases and diseases of infancy and childhood, infectious diseases and environmental injury.
A bibliography is provided for supplemental reading and histopathology atlas.
At the end of the course there is a test based on lectures, presentations, and required reading.
Course/Module aims:
1. To grant knowledge about cellular/tissue/organ morphological changes in reaction to stress/injury.
2. To understand pathological processes and their mechanism, including: inflammation; autoimmunity, neoplasia, etc.
3. To understand the relation between morphological and functional changes.
4. To understand the relation between morphological changes and clinical presentation as a bases for clinical and therapeutic medicine.
Learning outcomes - On successful completion of this module, students should be able to:
1. Recall pathological terminology
2. Outline cellular/tissue/organ adaptation to stress/injury, and associate them with clinical
presentation in various diseases.
3. Describe the pathological processes observed in inflammation, repair, hemodynamic disorders,
infectious diseases, autoimmune diseases and environmental injury
4. Recognize certain genetic and metabolic diseases
5. Classify neoplasms according to customary nomenclature, and recognize common moleculargenetic
alterations and risk factors underlying neoplasia.
Attendance requirements(%):
80% Minimum.
Teaching arrangement and method of instruction:
Integration of frontal lectures, presentations and required reading in the course book.
Course/Module Content:
• Introduction
• Cellular Responses to Stress and Toxic Insults:Adaptation, Injury, and Death
• Inflammation and Repair
• Hemodynamic Disorders, Thromboembolic Disease, and Shock
• Genetic and metabolic disorders, and diseases of Infancy and Childhood
• Diseases of the Immune System, including amyloidosis
• Neoplasia: Morphological/molecular features (genotype-phenotype relation)
• Infectious Diseases
• Environmental and Nutritional Diseases, including radiation injury
Required Reading:
Kumar, Abbas, Aster. Robbins & Cotran Pathologic Basis of Disease, 10th Edition 2021
Additional Reading Material:
Kumar, Abbas, Aster. Robbins Basic Pathology, 10th Edition 2018
Klatt, Robbins and Cotran Atlas of Pathology, 4th Edition 2020
Grading Scheme :
Written / Oral / Practical Exam / Home Exam 100 %
Additional information:
Changes in teaching arrangement/method of instruction, teaching staff and/or course assessment may occur subject to staff considerations or unpredictable events.
The course, except for the issue of slide laboratory, is identical to course 96214, including the lecturers list.
Subject to constraints the finalizing test may be in an online format.
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