Syllabus - Bioinformatics: Basic Sequence Analysis Tools (94665)

Syllabus Bioinformatics: Basic Sequence Analysis Tools - 94665
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Last update 10-07-2018
HU Credits: 3 Degree/Cycle: 1st degree (Bachelor) Responsible Department: Bio-Medical Sciences Semester: 1st Semester Teaching Languages: Hebrew Campus: Ein Karem Course/Module Coordinator: Tamar Kahan Coordinator Email: tamar.kahan@huji.ac.il Coordinator Office Hours: Teaching Staff: Dr. Tamar Kahan Prof Itamar Simon Prof Ora Furman-Schueler Ms. Britny Blumenfeld Mr. Mr. Maxim Mogilevsky Course/Module description: The course is based on lectures with demonstration and hands-on practice by the students. The students are introduced to relevant bioinformatics databases and common sequence analysis tools. Course/Module aims: Provide students with skills to use biological molecule sequence databases and analysis tools, and tools to assess their quality. Learning outcomes - On successful completion of this module, students should be able to: Conduct research of DNA, RNA and protein sequences; use tools for comparison and characterization of sequences; identify functional domains and predict the structure of molecules; explore the genomic context of genes; basic analysis of gene expression using databases of expression profiles. Attendance requirements(%): 100 Teaching arrangement and method of instruction: Lectures and exercises with live demonstrations and hands-on practice. Course/Module Content: • Common sequence and knowledge databases and a mechanism for assessing their quality • Algorithms and tools for DNA and protein pairwise and multiple sequence alignment • Searching text and sequence databases • Sequence motifs and databases: tools for sequence analysis and classification; tools for de novo definition of motifs. • Protein structure visualization and prediction • Genomic databases and genome browsers • NGS and microarray sequence databases and common analysis tools for expression profiling Required Reading: None Additional Reading Material: Course/Module evaluation: End of year written/oral examination 0 % Presentation 0 % Participation in Tutorials 0 % Project work 0 % Assignments 20 % Reports 0 % Research project 70 % Quizzes 10 % Other 0 % Additional information: All exercises and lectures take place at a PC classroom. Students get hands-on experience.

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