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Syllabus From Molecules to Circuits - 76900
עברית
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Last update 07-03-2024
HU Credits: 3

Degree/Cycle: 2nd degree (Master)

Responsible Department: Brain Science: Computation & Information Proc.

Semester: 2nd Semester

Teaching Languages: English

Campus: E. Safra

Course/Module Coordinator: Dr. Yoav Adam

Coordinator Email: yoav.adam@mail.huji.ac.il

Coordinator Office Hours: by appointment

Teaching Staff:
Dr. Yoav Adam,
Dr. Eran Lottem,
Dr. Naomi Habib

Course/Module description:
The course will deal with advanced topics in molecular, cellular, and circuit neurophysiology.

Course/Module aims:
The course will provide advanced knowledge of molecular, cellular, and circuit neurophysiology, focusing on recent, state-of-the-art literature.

Learning outcomes - On successful completion of this module, students should be able to:
Critically read and present state of the art papers on molecular, cellular, and microcircuit neuroscience

Attendance requirements(%):

Teaching arrangement and method of instruction: Frontal lectures
Reading chores

Course/Module Content:
Part 1 - Yoav Adam: Advanced topics in synaptic-cellular neurophysiology. (a) Basic and advanced topics in synaptic plasticity and its involvement in hippocampal place cell formation. (b) other modes of neuronal plasticity - plasticity of excitability, homeostatic plasticity, adult neurogenesis. (c) Dendritic computations
Parts 2 – Naomi Habib: Cellular and molecular processes underlying brain functions and diseases, and the advanced new technologies to measure and manipulate cells on the genetic and epigenetic level. The processes covered will include brain plasticity and addiction; development; psychiatric disorders (Major depression disorder); Aging and neurodegeneration (Alzheimer’s disease); neuroimmunology.
Part 3 – Eran Lottem: We will explore the structure and function of cortical microcircuits, focusing primarily on the primary visual cortex as an exemplar for how interactions among different types of neurons give rise to sophisticated computations.
Part 4 – Introduction to neuroanatomy including hands-on brain dissections

Required Reading:
Two research papers every week

Additional Reading Material:

Grading Scheme :
Written / Oral / Practical Exam 50 %
Active Participation / Team Assignment 5 %
Presentation / Poster Presentation / Lecture 45 %

Additional information:
 
Students needing academic accommodations based on a disability should contact the Center for Diagnosis and Support of Students with Learning Disabilities, or the Office for Students with Disabilities, as early as possible, to discuss and coordinate accommodations, based on relevant documentation.
For further information, please visit the site of the Dean of Students Office.
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