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Syllabus Computational Biostatistics - 72942
עברית
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Last update 08-08-2021
HU Credits: 3

Degree/Cycle: 1st degree (Bachelor)

Responsible Department: Life Sciences

Semester: 1st Semester

Teaching Languages: Hebrew

Campus: E. Safra

Course/Module Coordinator: Liran Carmel

Coordinator Email: liran.carmel@huji.ac.il

Coordinator Office Hours:

Teaching Staff:
Prof Liran Carmel,
Ms. Chen Leibson

Course/Module description:
We will study important statistical methods that are frequently encountered in analyses of biological data. Emphasis will be given to the mathematical foundations of the methods.

Course/Module aims:
Knowledge of statsitical tools required for analysis of biological data, for researchers with computational orientation.

Learning outcomes - On successful completion of this module, students should be able to:
Apply the appropriate statistical analyses required in their particular research.

Attendance requirements(%):

Teaching arrangement and method of instruction: Lectures + forntal exercises + excercises

Course/Module Content:
1. Formal theory of hypothesis testing.
2. Estimators: point estimators, interval estimators, properties of estimators, basic estimators.
3. Data sampling, experimental design, analysis of variance.
4. ANOVA test, post-hoc tests.
5. Multiple comparisons: Bonferroni, FDR
6. Ranked statistics: U-test, Wilcoxon test and related tests.
7. Linear regression: one-dimensional regression, multiple regression, logistic regression.
8. Dimensionality reduction: PCA, t-SNE.
9. Analysis of contingency tables: hypergeometric test, Fischer exact test.
10. Randomization tests: Bootstrap, jackknife.
11. Markov models and its applications in Biology.

Required Reading:
none

Additional Reading Material:

Course/Module evaluation:
End of year written/oral examination 80 %
Presentation 0 %
Participation in Tutorials 0 %
Project work 0 %
Assignments 20 %
Reports 0 %
Research project 0 %
Quizzes 0 %
Other 0 %

Additional information:
 
Students needing academic accommodations based on a disability should contact the Center for Diagnosis and Support of Students with Learning Disabilities, or the Office for Students with Disabilities, as early as possible, to discuss and coordinate accommodations, based on relevant documentation.
For further information, please visit the site of the Dean of Students Office.
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