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HU Credits:
3
Degree/Cycle:
1st degree (Bachelor)
Responsible Department:
Life Sciences (Biology)
Semester:
2nd Semester
Teaching Languages:
Hebrew
Campus:
E. Safra
Course/Module Coordinator:
Prof Nayef Jarrous
Coordinator Office Hours:
By appointment
Teaching Staff:
Prof Nayef Jarrous
Prof Rotem Karni
Course/Module description:
The course is intended for undergraduate students in life and medical sciences. It focuses on molecular genetics/biology of transcription, processing of RNA and protein translation in animal cells. An emphasis will be placed on small molecules of RNA and their roles in regulation of the aforementioned biological processes.
Course/Module aims:
Formation of strong background for continuation of advanced studies in the future. The course will provide vast scientific information and tools for analytical thinking in molecular biology for undergraduate students. The course will also allow understanding of the structure-function relationship of RNA in the cell.
Learning outcomes - On successful completion of this module, students should be able to:
1. Describe and explain transcription, processing of RNA and protein translation 2. Describe and analyze regulatory mechanisms of these processes 3. Read and evaluate scientific research papers in molecular biology.
Attendance requirements(%):
None
Teaching arrangement and method of instruction:
Lecture
Course/Module Content:
- RNA World Hypothesis
- Structure and function of catalytic RNA
- Selection and evolution of RNA in vitro
- Gene transcription by RNA polymerase I and epigenetics by small RNA
- Gene transcription by RNA polymerase III and regulation by small RNAs.
- mRNA splicing
- Regulation of alternative mRNA splicing
- Protein translation
- Regulation of translation
- Cancer and regulation of splicing and translation
- Genome research
Required Reading:
Textbook: Genes IX by Benjamin Lewin
Additional Reading Material:
Research articles
Course/Module evaluation:
End of year written/oral examination 100 %
Presentation 0 %
Participation in Tutorials 0 %
Project work 0 %
Assignments 0 %
Reports 0 %
Research project 0 %
Quizzes 0 %
Other 0 %
Additional information:
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