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HU Credits:
5
Degree/Cycle:
1st degree (Bachelor)
Responsible Department:
Life Sciences
Semester:
2nd Semester
Teaching Languages:
Hebrew
Campus:
E. Safra
Course/Module Coordinator:
Prof Eran Meshorer
Coordinator Office Hours:
By appointment
Teaching Staff:
Dr. Oren Ram
Dr. Tamar Avin Wittenberg
Prof Eran Meshorer
Ms.
Ms.
Ms.
Ms.
Course/Module description:
The course discusses the structure of macro-molecules and DNA in particular; genome architecture; chromatin structure; functional/structure of the eukaryotic genome; transcription and regulation of transcription in prokaryotes and eukaryotes; transcriptional regulation; The structural basis for DNA recognition by transcription factors; RNA processing; translation; micro-RNAs; transgenic systems; recombinant DNA, and introduction to cellular differentiation. High-throughput methods: next generation sequencing and mass-spectrometry
Course/Module aims:
Acquire tools to analyze problems in molecular biology
Learning outcomes - On successful completion of this module, students should be able to:
Students will have acquired the ability to answer key questions in molecular biology
Attendance requirements(%):
Attendance is required in exercises
Teaching arrangement and method of instruction:
Lecture and exercise
Course/Module Content:
1. Introduction (DNA, protein nature, Molecular Biology Dogma)
2. Structure of Macromolecules
3. Transcription I
4. Transcription II
5. Translation I
6. Translation II
7. Databases and software
8. RNA processing
9. Alternative splicing & RNA editing
10. RNA stability
11. Regulatory RNAs
12. Complexity
13. Transgenic engineering
Required Reading:
Selected chapters in: Mol Biol Cell, 6TH Ed.
Additional Reading Material:
-
Course/Module evaluation:
End of year written/oral examination 90 %
Presentation 0 %
Participation in Tutorials 0 %
Project work 0 %
Assignments 10 %
Reports 0 %
Research project 0 %
Quizzes 0 %
Other 0 %
Additional information:
None
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