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HU Credits:
4
Degree/Cycle:
1st degree (Bachelor)
Responsible Department:
chemistry
Semester:
1st Semester
Teaching Languages:
Hebrew
Campus:
E. Safra Ein Karem
Course/Module Coordinator:
Norman Metanis
Coordinator Office Hours:
Upon demand
Teaching Staff:
Dr. Norman Metanis
Ms. Avia leader
Ms.
Ms. rebecca dardashti
Ms. yuval tarrab
Ms. Nitzan Ganot
Course/Module description:
Introduction to organic chemistry, compounds, reactions and mechanisms.
Course/Module aims:
To learn the fundamentals of organic chemistry
Learning outcomes - On successful completion of this module, students should be able to:
• Analyze and apply stereochemistry, isomerism and conformational considerations.
• Describe and evaluate the structure and reactivity of alkanes, alkenes, alkyl halides, alcohols, aromatic compounds, carbonyl compounds and carboxylic acid derivatives
• Assess reaction mechanisms
• Apply the concept of electrophile-nucleophile relationship in organic reactions
• Apply addition, elimination and substitution (electrophilic and nucleophilic) reactions to various organic molecules
• Demonstrate the practical skills required for organic synthesis.
Attendance requirements(%):
No Attendance is required
Teaching arrangement and method of instruction:
lectures and exercises
Course/Module Content:
• Electronic structure and bonding acids and bases (mandatory reading from the course book, overview).
• An introduction to organic compounds; nomenclature, properties, structures: Alkanes, isomers, nomenclature of alkyl substituents, cycloalkanes, alkyl halides, conformations.
• Alkenes; structure, nomenclature, reactivity: Electrophilic addition to alkenes, carbocation stability, delocalization of electrons, Markovnikov's Rule, carbocation rearrangements.
• Stereochemistry: Isomers, cis-trans, enantiomers, diastereomers, meso compounds, stereochemistry of electrophilic addition reactions to alkenes.
• Delocalization and resonance, Dienes: Benzene, stability contributed by resonance, nomenclature, structure, isomers and reactions of dienes.
• Reactions of alkanes.
• Substitutions and eliminations; alkyl halides, Griniard reactions.
• Aromaticity: Definition, stability of aromatic compounds, reactions of aromatic compounds.
• Carbonyl compounds: Definition, structure, properties, reaction of carbonyl compounds.
Required Reading:
Electronic structure and bonding acids and bases; according to chapters of 4th edition:
1: Mandatory self reading (Background of Basic Chemistry; not part of this course)
2: An introduction to organic compounds; nomenclature, properties, structures (60-94)
3-4: Alkenes; structure, nomenclature, reactivity (3: 111-126, 135-138; recommended: 126-135; 4: 141-145, 147-181)
5: Stereochemistry (182-237)
6: Alkynes (238-246, 249, 250-254, 254-262)
7: Delocalization and resonance (263-275, 278-286)
8: Dienes (298-308, 313-314, 315-317)
9: Reactions of alkanes (338-340, 346-349)
10-12: Substitutions and eliminations; alkyl halides, alcohols, ethers, epoxides, Griniard reactions (10: 360-390; 11: 400-417, 422-436; 12: 437-457, 466-470)
15: Aromaticity (594-610, 612-616)
17-19: Carbonyl compounds (17: 670-675, 676-677, 681-682, 683-695, 695-697, 702-706, 710-713; 18: 731-740, 743-750, 753, 755-757, 761-766, 769; 19: 788-796, 799-800, 804-816, 818-825)
Bioorganic compounds; carbohydrates, proteins, lipids, nucleic acids (22: 921-926, 934-937, 943-949; 23: 959-964, 973-976, 989-993; 26: 1075-1079, 1082-1083, 1097-1098; 27: 1106-1110, 1118-1122, 1128)
Additional Reading Material:
Course/Module evaluation:
End of year written/oral examination 100 %
Presentation 0 %
Participation in Tutorials 0 %
Project work 0 %
Assignments 0 %
Reports 0 %
Research project 0 %
Quizzes 0 %
Other 0 %
Additional information:
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