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| Last update 23-01-2024 |
HU Credits:
5
Degree/Cycle:
1st degree (Bachelor)
Responsible Department:
Chemistry
Semester:
1st Semester
Teaching Languages:
Hebrew
Campus:
E. Safra
Course/Module Coordinator:
Prof. Ahmad Masarwa
Coordinator Office Hours:
Upon demand
Teaching Staff:
Prof Ahmad Masarwa,
Mr. Yuval Rahav,
Mr. Sagi Ezov
Course/Module description:
Introduction to organic chemistry, compounds, reactions and mechanisms.
Course/Module aims:
To learn the fundamentals of organic chemistry
Learning outcomes - On successful completion of this module, students should be able to:
• Analyze and apply stereochemistry, isomerism and conformational considerations.
• Describe and evaluate the structure and reactivity of alkanes, alkenes, alkyl halides, alcohols, aromatic compounds, carbonyl compounds and carboxylic acid derivatives
• Assess reaction mechanisms
• Apply the concept of electrophile-nucleophile relationship in organic reactions
• Apply addition, elimination and substitution (electrophilic and nucleophilic) reactions to various organic molecules
• Demonstrate the practical skills required for organic synthesis.
Attendance requirements(%):
0%
Teaching arrangement and method of instruction:
Lecture and Exercise
Course/Module Content:
• Electronic structure and bonding acids and bases (mandatory reading from the course book, overview).
• An introduction to organic compounds; nomenclature, properties, structures: Alkanes, isomers, nomenclature of alkyl substituents, cycloalkanes, alkyl halids, ethers, alcohols, amines, conformations.
• Alkenes; structure, nomenclature, reactivity: Electrophilic addition to alkenes, carbocation stability, delocalization of electrons, Markovnikov's Rule, carbocation rearrangements, anti Markovnikov addition, radical addition.
• Stereochemistry: Isomers, cis-trans, enantiomers, diastereomers, meso compounds, stereochemistry of electrophilic addition reactions to alkenes.
• Alkynes: Nomenclature, structure, properties, addition reactions of alkynes, acidity of a hydrogen bonded to an sp hybridized carbon.
• Delocalization and resonance, Dienes: Benzene, stability contributed by resonance, nomenclature, structure, isomers and reactions of dienes.
• Reactions of alkanes.
• Substitutions and eliminations; alkyl halides, alcohols, ethers, epoxides, Griniard reactions.
• Aromaticity: Definition, stability of aromatic compounds, reactions of aromatic compounds.
• Carbonyl compounds: Definition, structure, properties, reaction of carbonyl compounds.
• Oxidation-reduction- minor.
• Bioorganic compounds; carbohydrates, proteins, lipids, nucleic acids- introduction.
Required Reading:
Electronic structure and bonding acids and bases; according to chapters of 4th edition:
1: Mandatory self reading (Background of Basic Chemistry; not part of this course)
2: An introduction to organic compounds; nomenclature, properties, structures (60-94)
3-4: Alkenes; structure, nomenclature, reactivity (3: 111-126, 135-138; recommended: 126-135; 4: 141-145, 147-181)
5: Stereochemistry (182-237)
6: Alkynes (238-246, 249, 250-254, 254-262)
7: Delocalization and resonance (263-275, 278-286)
8: Dienes (298-308, 313-314, 315-317)
9: Reactions of alkanes (338-340, 346-349)
10-12: Substitutions and eliminations; alkyl halides, alcohols, ethers, epoxides, Griniard reactions (10: 360-390; 11: 400-417, 422-436; 12: 437-457, 466-470)
15: Aromaticity (594-610, 612-616)
16: Reactions of aromatic compounds (622-646, 653-656)
17-19: Carbonyl compounds (17: 670-675, 676-677, 681-682, 683-695, 695-697, 702-706, 710-713; 18: 731-740, 743-750, 753, 755-757, 761-766, 769; 19: 788-796, 799-800, 804-816, 818-825)
20: Oxidation-reduction (841-843, 845, 846, 848, 850, 853, 855, 858, 859, 861)
22,23,26,27
Bioorganic compounds; carbohydrates, proteins, lipids, nucleic acids (22: 921-926, 934-937, 943-949; 23: 959-964, 973-976, 989-993; 26: 1075-1079, 1082-1083, 1097-1098; 27: 1106-1110, 1118-1122, 1128)
Additional Reading Material:
Grading Scheme :
Written / Oral / Practical Exam / Home Exam 100 %
Additional information:
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Students needing academic accommodations based on a disability should contact the Center for Diagnosis and Support of Students with Learning Disabilities, or the Office for Students with Disabilities, as early as possible, to discuss and coordinate accommodations, based on relevant documentation.
For further information, please visit the site of the Dean of Students Office.
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