HU Credits:
4
Degree/Cycle:
1st degree (Bachelor)
Responsible Department:
School of Pharmacy
Semester:
1st Semester
Teaching Languages:
Hebrew
Campus:
Ein Karem
Course/Module Coordinator:
Dr Orit Cohen
Coordinator Office Hours:
the course forum is available for any question
Teaching Staff:
Dr. Orit Cohen
Course/Module description:
The course is intended for science graduates to refresh the knowledge of course participants in the analytical methods commonly used in chemistry and pharmacy laboratories. Participants will study wet analytical methods like titrations and spectral methods like NMR, FTIR, UV and more.
Course/Module aims:
The course provides basic background to quantitative analytical methods commonly used in chemical and pharmaceutical laboratories. In addition, background and practice in useful spectral methods will be provided.
Learning outcomes - On successful completion of this module, students should be able to:
At the end of this course;
The students will understand the principles of analytical methods used in main quantitative determinationד.
The students will be able to analyze the results in the lab and the possible error sources.
The students will be able to choose a good analytical method for a given compound.
Attendance requirements(%):
Teaching arrangement and method of instruction:
The course will be taught in the first semester by distance learning using the Moodle program. The participants are required to study each week a chapter containing recorded lectures and exercises for solving and submitting. Every week there will be a zoom meeting with the course coordinator who will present some exercises.
Course/Module Content:
List of topics:
1. Different concentration units and dilution; molarity, molality, volume and weight percentage, ppm and ppb.
2. Acids and bases: Bronshtad acids and bases, equilibrium constants of acids and bases, acids and bases in nonaqueous solvents, the ionization of water, pH, ionic strength and activity, indicators, neutralization, buffers.
3. Titrations of acids and bases: Basic terms in volumetric analysis, types of titration, standards, calculation of titration curves for strong and weak acids and bases and for polyprotic acids, equivalent concentrations and the normal.
4. Solubility of insoluble salts and product of solubility, precipitation titrationsץ 5. EDTA complexes with metals.
6. Redox: Oxidising and reducing reagents, balancing redox processes, redox titrations, equivalent concentration in redox reactions, introduction to electrolchemical cells (electrolytic and Galvanic), glass electrode and pH measurement.
6. Introduction to spectroscopy: Absorption spectroscopy in UV, Beer-Lambert law and deviations from this rule.principals and quantitive uses.
7. Principles of separation by partition: chromatography and extraction.
8. Introduction to IR spectroscopy
9. Introduction NMR chromatography
Required Reading:
Course presentations and additional information that will be loaded in the Moodle.
Additional Reading Material:
D.C. Harris
Quantitative Chemical
Analysis
any edition
Grading Scheme :
Written / Oral / Practical Exam 90 %
Submission assignments during the semester: Exercises / Essays / Audits / Reports / Forum / Simulation / others 10 %
Additional information:
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