The Hebrew University Logo
Syllabus ORGANIC CHEMISTRY B - 64311
close window close
PDF version
Last update 03-09-2018
HU Credits: 4

Degree/Cycle: 1st degree (Bachelor)

Responsible Department: School of Pharmacy

Semester: 1st Semester

Teaching Languages: Hebrew

Campus: Ein Karem

Course/Module Coordinator: Dr. Dmitry Tsvelikhovsky

Coordinator Email:

Coordinator Office Hours: In coordination with a lecturer

Teaching Staff:
Prof Dmitry Tsvelikhovsky
Mr. David Lankri

Course/Module description:
The course provides students with basic knowledge in organic chemistry. The course includes terminology methods, the properties and important reactions of families with the following functional groups: alkanes, alkenes and Alkynes, Halo-alkanes, aromatic systems, alcohols, ethers, aldehydes and ketones.

Course/Module aims:
The course provides the students with basic knowledge of organic chemistry that will enable them to cope with understanding the synthesis concepts

Learning outcomes - On successful completion of this module, students should be able to:
On successful completion of this module, students should be able to: 1) Identify functional groups and remember their most important reactions. 2) Examine an organic molecule and construct its systematic name. 3) Suggest reagents and plan a practical way to synthesize desired organic molecules.

Attendance requirements(%):

Teaching arrangement and method of instruction: 3 hours lecture and one hour exercise

Course/Module Content:
1. Reactions of Alcohols, Ethers, Epoxides and Thiols
- Nucleophilic substitution reactions: forming Alkyl halides
- Elimination reactions: Dehydration
- Oxidation
- Reactions of ethers and epoxides
- Thiols

2. Organometallic Compounds

3. Reactions of Aldehydes and Ketones
- Nomenclature of aldehydes and ketones
- Structures
- Physical properties
- Relative reactivity of carbonyl compounds
- Reaction with nucleophiles

4. Reactions at the -Carbon of Carbonyl Compounds
- Acidity of an -Hydrogens
- Keto-Enol Tautomerism
- Halogenation of the -Carbon of Aldehydes and Ketones
- Enolate ion
- Alkylation of the -Carbon of Aldehydes and Ketones
- Enamines
- Michael Reactions
- Aldol addition
- Claisen Condensation

5. Reactions of Carboxylic Acids and Carboxylic Derivatives
- Nomenclature
- Structures
- Physical properties
- Relative reactivity of acids and derivatives
- Nucleophilic additions-elimination reactions
- Acyl chlorides
- Esters
- Hydrolysis and Esterification

6. Aromatic compounds
- Nomenclature
- Reactions

7. Dienes
- Nomenclature
- Reactions

Required Reading:
Textbook-Paula Yurkanis Bruice (updated version)

Additional Reading Material:

Course/Module evaluation:
End of year written/oral examination 100 %
Presentation 0 %
Participation in Tutorials 0 %
Project work 0 %
Assignments 0 %
Reports 0 %
Research project 0 %
Quizzes 0 %
Other 0 %

Additional information:
The obligation to submit 80% of the exercises.
Students needing academic accommodations based on a disability should contact the Center for Diagnosis and Support of Students with Learning Disabilities, or the Office for Students with Disabilities, as early as possible, to discuss and coordinate accommodations, based on relevant documentation.
For further information, please visit the site of the Dean of Students Office.