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HU Credits:
2
Degree/Cycle:
1st degree (Bachelor)
Responsible Department:
School of Pharmacy
Semester:
1st Semester
Teaching Languages:
Hebrew
Campus:
Mt. Scopus
Course/Module Coordinator:
Amiram Goldblum
Coordinator Office Hours:
email
Teaching Staff:
Prof Amiram Goldblum
Course/Module description:
The Chemical and Biological basis of drug actions and the main methods for discovery and design of drugs. Understanding the structures and properties of drug molecules and their interactions with biological "targets" to help alleviate disease
Course/Module aims:
Understanding of the basics of "medicinal chemistry" - in particular the drug development which requires chemical appreciation of the binding between atoms and molecules and the relevance to the drugs' effects on biological systems
Learning outcomes - On successful completion of this module, students should be able to:
An ability to read articles dealing with drug action, in popular science magazines and journals
Attendance requirements(%):
Teaching arrangement and method of instruction:
Frontal
Course/Module Content:
Introduction: what are drugs, what is rational discovery and design, "rational and "irrational" drugs. How are drugs discovered/designed in pharma companies, the contributions of computer studies, sources of information on molecules- crystal structures, "molecular libraries". Natural resources, Path of approvl of drugs bt FDA, Drug interactions, illegal drugs, pharmacology - pharmacokinetics and pharmacodynamics, ADME and toxicity
Required Reading:
No required readings, only recommnedations
Additional Reading Material:
Grading Scheme :
Additional information:
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