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HU Credits:
2
Degree/Cycle:
1st degree (Bachelor)
Responsible Department:
school of pharmacy
Semester:
2nd Semester
Teaching Languages:
Hebrew
Campus:
Ein Karem
Course/Module Coordinator:
Dr. Rachel Ta-Shma
Coordinator Office Hours:
Teaching Staff:
Dr. Rachel Ta-Shma
Course/Module description:
The course provides basic theoretical background to quantitative analytical methods accepted in chemical and pharmaceutical laboratories.
Course/Module aims:
See learning Outcomes
Learning outcomes - On successful completion of this module, students should be able to:
At the end of this course;
The students will understand the principles of analytical methods used in main quantitative determinationד.
The students will be able to analyze the results in the lab and the possible error sources.
The students will be able to choose a good analytical method for a given compound.
Attendance requirements(%):
100
Teaching arrangement and method of instruction:
Lecture and exercise
Course/Module Content:
List of topics:
1. Refreshing mathematical skills and some statistics: Scientific notation, value and units, units, systematic errors and random errors, normal error curve, average and standard deviation, the accumulation of errors, finding the best linear dependence between two variables and the correlation coefficient.
2. Different concentration units and dilution; molarity, molality, volume and weight percentage, ppm and ppb.
3. Acids and bases: Bronshtad acids and bases, equilibrium constants of acids and bases, acids and bases in nonaqueous solvents, the ionization of water, pH, ionic strength and activity, indicators, neutralization, buffers.
4. Titrations of acids and bases: Basic terms in volumetric analysis, types of titration, standards, calculation of titration curves for strong and weak acids and bases and for polyprotic acids, equivalent concentrations and the normal.
5. Solubility of insoluble salts and product of solubility, precipitation titrations, EDTA complexes with metals.
6. Redox: Oxidising and reducing reagents, balancing redox processes, redox titrations, equivalent concentration in redox reactions, introduction to electrolchemical cells (electrolytic and Galvanic), glass electrode and pH measurement.
7. Introduction to spectroscopy: Absorption spectroscopy in UV, Beer-Lambert law and deviations from this rule.
8. Introduction to chromatography: Principles of separation by partition, liquid chromatography LC and TLC.
Required Reading:
course presentations
Additional Reading Material:
D.C. Harris
Quantitative Chemical
Analysis
any edition
Course/Module evaluation:
End of year written/oral examination 90 %
Presentation 0 %
Participation in Tutorials 0 %
Project work 0 %
Assignments 10 %
Reports 0 %
Research project 0 %
Quizzes 0 %
Other 0 %
Additional information:
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