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HU Credits:
2
Degree/Cycle:
1st degree (Bachelor)
Responsible Department:
Enrichment Program for High School students
Semester:
Yearly
Teaching Languages:
Hebrew
Campus:
E. Safra
Course/Module Coordinator:
Shir Bahiri-Elitzur
Coordinator Office Hours:
Teaching Staff:
Ms. Shir Bahiri-Elitzur,
Ms. Larissa Fine
Course/Module description:
Introduction to synthetic biology - a link between the world of biology and the worlds of mathematics, engineering, computer science and bioinformatics
Course/Module aims:
Exposure and accessibility of topics at the forefront of research in the field of synthetic biology for the younger generation
Learning outcomes - On successful completion of this module, students should be able to:
Recognizing, analyzing, researching and solving problems in the biological world using biophysical and programming tools.
Emphasis on intracellular processes, diseases related to DNA
Attendance requirements(%):
90% Mandatory attendance (up to 3 sessions can be omitted)
Teaching arrangement and method of instruction:
In class
Course/Module Content:
Biological contents - enzymes, cellular theory, mitochondrion and energy transduction, the cell membrane and transfer of materials, DNA structure and its replication process, the cell cycle, and genetics, the central dogma of biology- transcription and translation processes.
Molecular methods - restriction enzymes, PCR, gel electrophoresis, plasmids, primer design, transformation, DNA sequencing
Computational biology methods - sequence alignment global and local, PSSM, Fitch algorithm (phylogenetic trees), codon usage bias indices (CAI, ENC), ribosome flow model
Advanced topics in synthetic biology - CRISPR, organs on a chip, synthetic genetic circuits, biosensors, bio-physical model of translation process, phages and ethics, vaccine research (Covid as a case study), Synthetic biology in the food industry, chosen topic of innovative research in the field
Labs - Enzymatic kinetics, genetic engineering, biosensors
Computational tools - Python workshop
Tours and guest lectures
Required Reading:
Non
Additional Reading Material:
Grading Scheme :
Essay / Project / Final Assignment / Referat 45 %
Presentation / Poster Presentation / Lecture/ Seminar / Pro-seminar / Research proposal 10 %
Submission assignments during the semester: Exercises / Essays / Audits / Reports / Forum / Simulation / others 40 %
Attendance / Participation in Field Excursion 5 %
Additional information:
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