HU Credits: 3

Degree/Cycle: 2nd degree (Master)

Responsible Department: Veterinary Medicine

Semester: 1st Semester

Teaching Languages: Hebrew

Campus: Rehovot

Course/Module Coordinator: Dr. Elad Eliahoo

Coordinator Email: elad.eliahoo@mail.huji.ac.il

Coordinator Office Hours: By appointment

Teaching Staff:
Dr. David Dan,
Dr. Caroline Noach,
Dr. ELAD ELIAHOO,
Dr. Sharon Karniely,
Dr. ASAF SOL,
Dr. ARIEL SOBARZO

Course/Module description:
viral diseases in the veterinary medicine

Course/Module aims:
Understanding of the mechanisms of interaction between the virus its host, how the virus causes the host or recovery factors or important viral diseases in veterinary medicine, a vaccine against the virus and the use of viruses in gene therapy.

Learning outcomes - On successful completion of this module, students should be able to:
1. The students will be able to describe the Host-Pathogen Interactions and their affect on the evolution of viruses.
2. When given a list of specific viral charterers, the students will be able to classify the virus according to its family.
3. When given a description of clinical presentation of a viral disease, the students will be able to identify the viral pathogen, its stages of replication and the pathogenesis of the disease in the infected animal, and vise versa.

Attendance requirements(%):
100

Teaching arrangement and method of instruction: Frontal lectures

Course/Module Content:
1. Introduction - Virus structure biology and virus assembly, classification of viruses, host-viral pathogen co-evolution.
2. Diagnostics methods of viral diseases
3. Introduction to Vaccinology + The development of viral vaccines - Molecular approach
4.Epidimiology and pathogenesis of viral diseases, Introduction to RNA viruses + RNA viruses
5. ssDNA viruses Parvoviridae, Circoviridea, Anelloviridea
6. Oncogenic DNA viruses - Papilomaviridae, Polyomaviridae
7. dsDNA viruses - Adenoviridae
8. latent viruses - Herpesviridae
9. megavirales - Poxviridae, Asfaviridae
10. non-cytolitic RNA viruses - Bornaviridae
11. Hepatitis viruses - Hepaeviridea
12. Rhabdovoridae
13. Arboviridae, Togaviridea, Bunyaviridea, Reoviridea, Flaviviridea
14. Orthomyxoviridae, Paramyxoviridae
15. Coronaviridae Picornaviridae,
16. Emerging Viruses, zoonotic viruses and viral-host interaction
17. Arteriviridae, Caliciviridae
18. Retroviridae

Required Reading:
1.Principles of Virology - Molecular Biology, Pathogenesis, and Control – Flint, Enquist, Krug, Racaniello, Skalka. ASM Press-1st edition, 2000, or 2nd edition 2004
2.Fundamental virology / editors- in –chief, Bernard N. Fields, David M. Knipe, Peter M. Howley. Raven Press- 4th edition, 2001.
3. Fenner's Veterinary Virology, 4th or 5th adition, N. Maclachlan Edward J Dubovi, Academic Press, November 2016
4. Veterinary Virology - Murphy, Gibbs, Horzinek, Studdert. Academic Press – 3rd edition, 1999.
5.Viral Pathogenesis and Immunity – Nathanson. Lippinkott – Raven Publishers, 2002

Additional Reading Material:
•https://www.moag.gov.il/vet/Yechidot/Apidmiology/maagar_baaley_chaim/Pages/default.aspx
• http://www.ivis.org/advances/Carter/toc.asp
• http://www.cdc.gov –
• http://www.oie.int/eng/OIE/en_oie.htm-
• http://www.ncbi.nlm.nih.gov/ICTVdb/-

Grading Scheme :
Written / Oral / Practical Exam 60 %
Presentation / Poster Presentation / Lecture/ Seminar / Pro-seminar / Research proposal 20 %
Mid-terms exams 20 %

Additional information:
Attendance is mandatory and non-justified absence will lead to reduction in score (up to 10%).
Pre-knowledge in fundamental virology is required.
Quizzes and final test will be held in the campus, but might be divert to online format dependent on the COVID19 crises and University guidance.
The tests will be multiple answers format with no external material allowed.
self learning material includes "Veterinary aspects in West-Nile virus outbreak in USA in 1999" (Podcast)