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HU Credits:
4
Degree/Cycle:
1st degree (Bachelor)
Responsible Department:
School of Pharmacy
Semester:
1st Semester
Teaching Languages:
Hebrew
Campus:
Ein Karem
Course/Module Coordinator:
Dr. Dmitry Tsvelikhovsky
Coordinator Office Hours:
In coordination with a lecturer
Teaching Staff:
Prof Dmitry Tsvelikhovsky
Mr. David Lankri
Course/Module description:
The course provides students with basic knowledge in organic chemistry. The course includes terminology methods, the properties and important reactions of families with the following functional groups: alkanes, alkenes and Alkynes, Halo-alkanes, aromatic systems, alcohols, ethers, aldehydes and ketones.
Course/Module aims:
The course provides the students with basic knowledge of organic chemistry that will enable them to cope with understanding the synthesis concepts
Learning outcomes - On successful completion of this module, students should be able to:
On successful completion of this module, students should be able to: 1) Identify functional groups and remember their most important reactions. 2) Examine an organic molecule and construct its systematic name. 3) Suggest reagents and plan a practical way to synthesize desired organic molecules.
Attendance requirements(%):
None
Teaching arrangement and method of instruction:
3 hours lecture and one hour exercise
Course/Module Content:
1. Reactions of Alcohols, Ethers, Epoxides and Thiols
- Nucleophilic substitution reactions: forming Alkyl halides
- Elimination reactions: Dehydration
- Oxidation
- Reactions of ethers and epoxides
- Thiols
2. Organometallic Compounds
3. Reactions of Aldehydes and Ketones
- Nomenclature of aldehydes and ketones
- Structures
- Physical properties
- Relative reactivity of carbonyl compounds
- Reaction with nucleophiles
4. Reactions at the -Carbon of Carbonyl Compounds
- Acidity of an -Hydrogens
- Keto-Enol Tautomerism
- Halogenation of the -Carbon of Aldehydes and Ketones
- Enolate ion
- Alkylation of the -Carbon of Aldehydes and Ketones
- Enamines
- Michael Reactions
- Aldol addition
- Claisen Condensation
5. Reactions of Carboxylic Acids and Carboxylic Derivatives
- Nomenclature
- Structures
- Physical properties
- Relative reactivity of acids and derivatives
- Nucleophilic additions-elimination reactions
- Acyl chlorides
- Esters
- Hydrolysis and Esterification
6. Aromatic compounds
- Nomenclature
- Reactions
7. Dienes
- Nomenclature
- Reactions
Required Reading:
Textbook-Paula Yurkanis Bruice (updated version)
Additional Reading Material:
-
Course/Module evaluation:
End of year written/oral examination 100 %
Presentation 0 %
Participation in Tutorials 0 %
Project work 0 %
Assignments 0 %
Reports 0 %
Research project 0 %
Quizzes 0 %
Other 0 %
Additional information:
The obligation to submit 80% of the exercises.
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